Directions and Map

Map and directions from Hyatt Regency website:

Directions

From the Buffalo-Niagara International Airport (9 miles):
Take the Kensington Expressway (33W) to Goodell Street exit. Follow overhead
Pearl St. signs and bear left onto Pearl Street. Hotel is approximately
three blocks further on left side of Pearl and West Huron Streets.

If you are coming from...

EAST: Follow I-90 West to exit #51W ( Rt-33 West).  The expressway will end,
placing you on Goodell Street West. Bear to the left onto Pearl Street 
Rt 5 west). Hyatt Regency Buffalo is located three blocks down on the
left .

WEST: Follow I-90
East to I-190 North.  Exit on Niagara Street and turn right (heading
South). Turn left after the blinking light onto West Huron Street).
Turn right onto Pearl Street.   Hyatt Regency Buffalo will be on the
immediate left side.

NORTH: Follow I-90
South.  Exit on Niagara Street and turn right (heading south). Turn
left after the blinking light onto West Huron Street. Turn right onto
Pearl Street. Hyatt Regency Buffalo will be on the immediate left  side.

SOUTH: Follow directions for West (above) after the following:

NEW YORK CITY:  Take I-87 North to I-90 West, then follow directions from East (above)

BOSTON, ALBANY, ROCHESTER: Follow directions from East (above)

CLEVELAND: Follow directions from West (above)

PENNSYLVANIA:  Take the  Pennsylvania Turnpike to 79 North to I-90 East. From there, follow directions from West (above)

DETROIT, WINDSOR: Take the 401 East to 403 East to QEW into Fort Erie. From there, follow directions from North (above)

TORONTO, HAMILTON:  Take the QEW to Fort Erie, then follow directions from North (above).